This compound adjective designates those who fight against God—opponents of divine purposes and rebels against deity. It combines the same elements as the verb θεομαχέω but in adjectival form, describing a characteristic quality rather than an action. Classical usage applied it to mythological giants who warred against the gods. Gamaliel uses it in Acts, warning the Sanhedrin that if the apostles' work is from God, opposing it would make them God-fighters—a battle they cannot win. The term suggests both futility and danger in resisting divine purposes.