At Golgotha, soldiers offered Jesus wine mixed with myrrh, but he refused it (Mark 15:23). The participle ἐσμυρνισμένος describes wine drugged with myrrh, likely intended to dull pain or awareness during crucifixion. Myrrh added bitter flavor and possible narcotic properties. Jesus's refusal to drink signals his determination to face death fully conscious, experiencing the cup of suffering completely. This contrasts with his later acceptance of sour wine (15:36), which was not medicated. The myrrhed wine represents an offered mercy Jesus deliberately declines to maintain clarity through his passion.